Zegavit

     

Zegavit caplets are supplements to meet the needs of vitamins and minerals, and help increase endurance and help maintain a healthy body. This supplement is a consumer product that can be purchased over the counter.

Drug composition;

-Vitamin E 30 IU.

-Vitamin C 750 mg.

-Vitamin B1 15 mg.

-Vitamin B2 15 mg.

-Niacinamide 100 mg.

-Vitamin B6 25 mg.

-Vitamin B12 12 mcg.

-Folic acid 0.4 mg.

-Calcium 20 mg.

-Pantothenic acid 20 mg.

-Zinc 20 mg.

Zegavit caplets contain vitamin E, vitamin C, vitamin B complex, calcium and zinc. This supplement can treat a variety of vitamin and mineral deficiency conditions due to lack of nutritional intake and can help speed up the recovery period after illness.In addition, this supplement can also meet the needs of vitamins and minerals in pregnant and lactating women, and help treat diseases that interfere with vitamin absorption, causing deficiency or deficiency of certain vitamins.

Active substance information

Vitamin B1 is a vitamin that is important in breaking down carbohydrates from food into products the body needs. Vitamin B1 is found in foods, such as cereals, whole grains, meat, and legumes, such as legumes.

Based on the work process of drugs in the body, vitamin B1 is known to have the following status:

-Absorption: Well absorbed from the gastrointestinal tract after oral administration.

-Distribution: Widely distributed in most body tissues and enters breast milk.

-Excretion: Excreted through urine.

-Vitamin B2 is needed for energy utilization from food and is important for maintaining normal tissue breathing. This vitamin is also required for the activation of vitamin B6 and the conversion of tryptophan to nicotinic acid, or the active form of vitamin B3.

Based on the work process of drugs in the body, vitamin B2 is known to have the following status:

-Absorption: Easily absorbed from the upper gastrointestinal tract.

-Distribution: Widely distributed, including erythrocytes and liver. Across the placenta and enters breast milk.

-Excretion: About 9% is excreted in the urine.

Vitamin B6 is necessary for maintaining proper function of sugars, fats and proteins in the body. Apart from that, this vitamin is also necessary for the growth and development of the brain, nerves, skin and many other parts of the body. Vitamin B6 is found in foods, such as meat, poultry, nuts, seeds, bananas and avocados.

Based on the work process of drugs in the body, vitamin B6 is known to have the following status:

-Absorption: Well absorbed from the gastrointestinal tract after oral administration.

-Distribution: Across the placenta and enters breast milk.

-Metabolism: Converted into pyridoxal phosphate and pyridoxamine phosphate, which are stored and metabolized mainly in the liver.

-Excretion: Excreted through urine.

Nicotinamide is a vitamin B3 derivative and is involved in several pathways of cellular metabolism, namely the breakdown of compounds or components in living cells to be converted into other forms, such as energy. This substance is also able to reduce inflammation significantly.

Based on the work process of drugs in the body, vitamin B3 is known to have the following status:

-Absorption: Easily absorbed from the gastrointestinal tract. The time when the drug reaches its highest plasma level (time to peak plasma concentration) is about 20-70 minutes.

-Distribution: Widespread in body tissues and enters breast milk.

-Metabolism: Metabolized in the liver.

-Excretion: Through urine. The time it takes for the drug to be excreted by the body from the initial half of the drug (elimination half-life) is about 45 minutes.

Vitamin B12 is needed to maintain the function and development of the brain, nerves, blood cells, and many other parts of the body. Vitamin B12 is needed by the body to work properly. This vitamin can be found in foods, such as meat, fish and dairy products.

Based on the work process of drugs in the body, vitamin B12 is known to have the following status:

-Absorption: Absorbed through the digestive tract.

-Distribution: In the blood, distributed and stored in the liver and bone marrow. Cross the placenta and a small amount passes into the breast milk.

-Excretion: Through bile and through urine.

Pantothenic acid or vitamin B5 can be found in plant and animal tissue. This vitamin has antioxidant properties that can protect the body from the effects of free radicals. Vitamin B5 is essential for growth and various metabolic functions, including the metabolism of carbohydrates, protein and fatty acids.

Based on the work process of drugs in the body, vitamin B5 is known to have the following status:

-Absorption: Easily absorbed from the gastrointestinal tract after oral administration.

-Distribution: Widely distributed in body tissues and breast milk.

-Excretion: About 70% is excreted in urine (unchanged) and 30% in feces.

Vitamin C (ascorbic acid) is an antioxidant which is important for tissue repair and collagen formation. In addition, vitamin C is involved in the formation of fat and protein, carbohydrate metabolism, iron absorption and storage, and cellular respiration.

Based on the work process of drugs in the body, vitamin C is known to have the following status:

-Absorption: Easily absorbed from the gastrointestinal tract.

-Distribution: Widely distributed in body tissues. Across the placenta and enters breast milk. Plasma protein concentration of about 25%.

-Metabolism: Metabolized into inactive metabolites, ascorbate-2-sulfate and oxalic acid.

-Excretion: Through urine (as an unchanged drug and inactive metabolites). The time it takes for the drug to be excreted by the body from the initial half of the drug (elimination half-life) is 10 hours.

Vitamin E is an antioxidant that can be found in foods, such as nuts, seeds, and green leafy vegetables. Vitamin E has various benefits for the body, for example maintaining the function of various organs of the body and as an antioxidant that helps slow down the process of cell damage.

Based on the work process of drugs in the body, vitamin E is known to have the following status:

-Absorption: The absorption of the digestive tract depends on the presence of bile. Only 20% to 60% of the vitamins obtained from food sources are absorbed. With increasing dosage, the absorbed vitamin E fraction decreases.

-Distribution: Distributed across all networks; stored in fat or adipose tissue.

-Metabolism: Metabolized in the liver.

-Excretion: Vitamin E is mainly excreted in the bile. Small amounts of metabolites are excreted in the urine.

-Indication (benefit) of the drug

-Maintain body resistance.

-Overcoming vitamin and mineral deficiencies.

-Overcoming the deficiency of vitamin B complex and vitamin C due to increased needs, such as during growth, as well as during pregnancy and breastfeeding.

   Helps overcome food absorption disorders and increase the intake of vitamin E, calcium and zinc in the body.Vitamin E is an antioxidant that can inhibit cell damage. This vitamin is found in foods, such as cereals, eggs, vegetable oils, meat, chicken, fruits, vegetables, and wheat germ oil.Vitamin C is important for gum and bone health. In addition, this vitamin also plays an important role in the formation of collagen, the foundation built by bone mineralization. Research shows increased levels of vitamin C contribute to greater bone density. In addition, vitamin C can also help the body absorb iron which is needed to produce red blood cells.Vitamin B complex functions to help produce energy, hormones, and cholesterol, maintain brain function, eyes, digestion, nerves, heart and cell metabolism, and form red blood cells.Minerals are needed by the body to keep bones, muscles, heart and brain working properly. Minerals are also essential for the manufacture of enzymes and hormones.Calcium helps muscles relax and contract. In addition, calcium is also important in nerve function, blood clotting, blood pressure regulation, and immune system health. Meanwhile, zinc is important for wound healing and is involved in many metabolic processes because it is part of many enzymes.